not really...they bring a wheel down onto the tire while it spins up to determine/simulate road force on the wheel. this will tell you if they did a good job balancing it. Most guys don't bother to try and line up the rim with the tire to eliminate the need for more weights.
Of course no tire or rim is absolutely true so they try and get as close as possible. If they did a shitty job balancing it then either the tire is shitty, rim bent or both